Publications with Heart Slices


Innovative Approaches to Safety Pharmacology
Authors: Michael K Pugsley

Cardiac tissue slices with prolonged survival for in vitro drug safety screening
Authors: Alexandra Bussek, Matthias Schmidt, Jessica Bauriedl, Ursula Ravens, Erich Wettwer, Horst Lohmann
Journal of Pharmacological and Toxicological Methods


Simultaneous measurement and modulation of multiple physiological parameters in the isolated heart using optical techniques.
Authors: Lee P, Yan P, Ewart P, Kohl P, Loew LM, Bollensdorff C.
PMID: 22886365 [PubMed – in process] PMCID: PMC3495582
Pflugers Arch. 2012 Oct;464(4):403-14. Epub 2012 Aug 12.

Field and action potential recordings in heart slices: Correlation with established IN VITRO and IN VIVo models
Authors: Herbert Himmel, Alexandra Bussek, Michael Hoffmann, Rolf Beckmann, Horst Lohmann, Matthias Schmidt, Erich Wettwer

Tissue Slices from Adult Mammalian Hearts as a Model for Pharmacological Drug Testing
Authors: Alexandra Bussek, Erich Wettwer, Thorsten Christ, Horst Lohmann, Patrizia Camelliti, Ursula Ravens


Innovation in safety pharmacology testing
Authors: M.K. Pugsley, R. Towart, S. Authier, D.J. Gallacher, M.J. Curtis
Journal of Pharmacological and Toxicological Methods
May 2011